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“ …. A single idea from the human mind can build cities…..

An idea can transform the world and rewrite all the rules…..” (Inception, 2010)

As stated in the quote from the 2010 blockbuster movie “Inception”, a single idea can indeed transform the whole world. Human history has witnessed many such ideas – Newton’s law of gravitation, Einstein’s theory of Relativity, Mendel’s theory of inheritance, Watson & Crick’s model of double-helix DNA and many more on the list to follow. For centuries scientific publications have been a platform to communicate any scientific ideas. Nevertheless scientific publication has also been a means to put ones views forward and initiate debates to address key issues such as global warming, biodiversity conservation, epidemics, etc. It is an undisputed fact that scientific progress serves as a development indicator of any nation and that is where scientific journal publication serves for national development.

Biotechnology Society of Nepal (BSN) had a vision to work towards journal publication especially in biotechnology and related life-sciences since its inception. In fact, biotechnology in Nepal is just toddling. Then, back in 2007, Nepal did not have even a single scientific journal published regularly that could document the precocious works of modern biotechnology. Research scientists from Nepal had to depend on international journals for their work to be recognized.

Despite many challenges, BSN took the lead to initiate Nepal Journal of Biotechnology (NJB) so as to address issues especially in biotechnology and its related domains of life-sciences. NJB got established in mid 2009 assembling a team of both young as well as distinguished scientists from Nepal and abroad to work for the publication of the journal. Later, towards the first quarter of 2010, NJB registered itself in Nepal Journal Online (Nepjol) as a peer reviewed open access journal.

NJB has recently published its inaugural issue on January 2011. There are 4 Original Research Articles, 1 Review Article, 2 articles under Short Communication and an editorial. More information about the journal can be found in

NJB and BSN together would like to thank all the authors of the published articles, the publication team, the editorial team and the members of the advisory board for a great team effort to initiate the publication of the journal. Indeed this has been a great milestone in the history of Nepali Biotechnology.

The following are the articles published.

Nepal Journal of Biotechnology, Vol 1, No 1 (2011)
Table of Contents:

Race for Excellence

Dipesh Dhakal

Original Research Articles

Information Theory and Multivariate Techniques for Analyzing DNA Sequence Data: An Example from Tomato Genes (1-8)

Bal K Joshi, Dilip R Panthee

An Evaluation of the Fungi Isolated from Sub-epidermal Region of Post-harvested Stored Wheat Grains (9-13)

Shiju Mathew,  George Thomas, Tufail Ahmad

Analysis of KatG Ser315Thr Mutation in Multidrug Resistant  Mycobacterium tuberculosis and SLC11A1 Polymorphism in Multidrug Resistance Tuberculosis in Central Development Region of Nepal Using PCR-RFLP Technique: A Pilot Study (14-21)

Raunak Shrestha, Rubin Narayan Joshi, Kriti Joshi, Bal Hari Poudel, Bhupal Govinda Shrestha

Development of PCR assay for targeting partial  lipL21  and  lipL41  gene of  leptospira  (22-30)
S Chandan, S Umesha,   SK Bhure, N Haraprasad, S Chandrashekar

Review Articles
Molecular differences between GM- and non-GM crops over-estimated? (31-48)

Klaus Ammann

Brief Communications

In vitro cultivation and regeneration of Solanum melongena  (L.) using stem, root and leaf explants (49-54)

Bishnu Pada Ray, Lutful Hassan,                Smreeti Kana Sarker

Biotechnology Growth Partnership: A Potential Flagship Program in S&T (55-58)

Raju Adhikari, Benu Adhikari

Kathmandu University Medical Journal has just published its latest issue at

Kathmandu University Medical Journal
Vol 8, No 2 (2010)
Table of Contents


Patient safety: Prevention during care (151-152)
A Vaidya

Gendericide: A scary truth (153)
NS Shrestha

Original Articles

Osteosynthesis of intercondylar humerus fracture using Bryan and Morrey
approach (154-157)
S Lakhey, S Sharma, RL Pradhan, BK Pandey, RR Manandhar, KP Rijal

Correlation of serum free prostate-specific antigen level with histological
findings in patients with prostatic disease (158-163)
M Lakhey, R Ghimire, R Shrestha, AD Bhatta

Antimicrobial susceptibility pattern and serotyping of Streptococcus
pneumoniae isolated from Kanti Children Hospital in Nepal (164-168)
B Rijal, S Tandukar, R Adhikari, NR Taludhar, PR Sharma, BM Pokharel, FC
Gami, A Shah, A Sharma, P Gauchan, JB Sherchand, T Burlakoti, HC Upreti, MK
Lalitha, K Thomas, M Steinhoff

Surgical abortion in second trimester: Initial experiences in Nepal
V Shrivastava, L Bajracharya, S Thapa

Effect of haemodynamic and metabolic predictors on echocardiographic left
ventricular mass in non-diabetic hypertensive patients (173-178)
N Gupta, P Karki, S Sharma, N Shrestha, P Acharya

Comparison of single versus multiple doses of antibiotic prophylaxis in
reducing post-elective Caesarean section infectious morbidity (179-184)
A Shakya, J Sharma

Objective voice analysis for vocal polyps following microlaryngeal
phonosurgery (185-189)
SiKC Toran, BK Lal

Prevalence of pharmacotherapy in the department of paediatric dentistry
KR Paudel, NK Sah, AK Jaiswal

Successes rate of endoscopic dacryocystorhinostomy at KMC (195-198)
S Shrestha, PK Kafle, S Pokhrel, M Maharjan, KC Toran

Use of double-balloon catheter in the management of epistaxis: A boon for
the periphery (199-202)
M Bista, C Baranwal, M Maharjan, P Kafle, S Shresth, KC Toran

Morbidity and early outcome of transurethral resection of prostate: A
prospective single-institute evaluation of 100 patients (203-207)
B Shrestha, JL Baidya

Upper gastro-intestinal bleeding: Aetiology and demographic profile based
on endoscopic examination at Dhulikhel Hospital, Kathmandu University
Hospital (208-211)
RB Gurung, G Joshi, N Gautam, P Pant, B Pokhrel, R Koju, TRS Bedi

Post partum haemorrhage: Prevalence, morbidity and management pattern in
Dhulikhel Hospital (212-215)
AS Dongol, A Shrestha, CD Chawla

Effect of preloading on haemodynamic of the patient undergoing surgery
under spinal anaesthesia (216-221)
J Singh, S Ranjit, S Shrestha, R Sharma, SB Marahatta

Near miss maternal morbidity and maternal mortality at Kathmandu Medical
College Teaching Hospital (222-226)
NS Shrestha, R Saha, C Karki

Acute appendicitis: Analysis of 518 histopathologically diagnosed cases at
the Kathmandu University Hospital, Nepal (227-230)
R Makaju, A Mohammad, A Shakya

Subclinical hypothyroidism in eastern Nepal: A hospital based study
V Rohil, AK Mishra, MK Shrewastwa, KD Mehta, M Lamsal, N Baral, S Majhi

Case Notes

Alport’s syndrome (238-240)
P Bastola, SN Joshi, M Chaudhary, DN Shah

Spigelian hernia (241-243)
TP Bhatia, P Ghimire, ML Panhani

Multiple intracranial tubercular abscesses in a child (244-246)
M Narang, S Gomber, L Upreti, S Dua

Retinoblastoma in a 37 years old man in Nepal: A case report (247-250)
A Shrestha, RC Adhikari, R Saiju

Chronic bilateral dislocation of temporomandibular joint (251-256)
S Shakya, R Ongole, KN Sumanth, CE Denny


An ultrasonographic evaluation of solitary muscular and soft tissue
cysticercosis (257-260)
P Sharma, S Neupane, M Shrestha, R Dwivedi, K Paudel

Initiating advanced laparoscopic surgery in a medical college hospital with
basic laparoscopic set up: Is it feasible and safe? (261-264)
PB Thapa

Variation of total serum cholesterol among the patient with thyroid
dysfunction (265-268)
P Risal, BR Maharjan, R Koju, RK Makaju, M Gautem

Review Articles
Halitosis: Much beyond oral malodor (269-275)
R Ongole, N Shenoy

Short Communication

Biomass combustion and potential health effects in the developing countries
SK Joshi, A Dahl, T Kristensen, P Roldin

Vaginal hysterectomy for pelvic organ prolapse in Nepal (281-284)
DK Sah, NR Doshi, CR Das

Book Reviews

A-Z of Practical Paediatrics (285)
Hemang Dixit

Clinical Examination Methods in Orthopedics (286)
Rajeev Raj Manandhar

The Short Textbook of Medical Microbiology (287)
Badri Thapa

A new issue of JNAMLS is available online:
VOL. 10 | NO. 1 | Dec. 2009
The below Table of Contents is available online at:


Evidence Based Laboratory Medicine
Binod K Yadav, Prajwal Gyawali, Rojeet Shrestha

Original Article

Status of Private Pathology Services in Kathmandu Valley, Kathmandu Nepal
Birendra R Tiwari, Shravan K Mishra, Binod K Yadav, Rojeet Shrestha, Jhabindra P Ghimire, Bal K Awal

Pattern of Dyslipidemia in Type 2 Diabetic Subjects in Eastern Nepal
Prashant Regmi, Prajwal Gyawali, Rojeet Shrestha, Manoj Sigdel, Kisun D Mehta, Shankar Majhi

Pancytopenia: A Memorable Manifestation of Megaloblastic Anemia
Ramesh K Makaju, Mohamad Ashraf, Sushama Bhatta, Ram Gurung, Babu R Pokharel

Relationship Between Pyuria and Bacteriuria in Suspected Urinary Tract Infection
Hari P Kattel, Shyam K Mishra, Jyoti Acharya, Aparna S Shah, Basistha P Rijal, Bharat M Pokhrel

Assessments of Urinary VMA Levels in Suspected Pediatric Cases of Catecholamines Producing Neurochromaffin Tumors
Rojeet Shrestha, Manoj Sigdel, Bibek Poudel, Prajwal Gyawali, Manoranjan Shrestha, Binod K Yadav, Vijay Sharma, Madhav Khanal, Bharat Jha

Serum Uric Acid Level in Obese and Non-obese Individuals
Binod K Yadav, Gokul B Chhetri, Bibek Poudel, Manoj Sigdel, Prajwal Gyawali, Prashant Regmi, Rojeet Shrestha

Parasitic Infection in School Children in Thimi Area, Kathmandu Valley
Swasti K Shrestha, Shiba K Rai, Ravi Vitrakoti, Prahlad Pokharel

Comparison between conventional Microscopy and Polymerase Chain Reaction (PCR) in malaria diagnosis
Shravan K. Mishra, Sohn KY, Shyam S Malla, Prerana Bajracharaya, Reena Lamichhane, Jeevan B Sherchan

Assessment of Thyroid Functions in Pregnant Subjects
Madhav Khanal, Sandhya Malla, Vijay Sharma, Prajwal Gyawali, Manoranjan Shrestha, Rojeet Shrestha

Study of Antimicrobial Resistance Pattern of Shigella sp. Isolated from Patients Visiting Western Regional Hospital, Pokhara
Jagat B Khadka, Jyoti Amatya, Archana Katuwal, Duk B Chhetri

Multi Drug Resistance Patterns of Urinary Isolates in a Tertiary Care Hospital of Nepal
Buddha B Basnet, Dharmendra Thakur, Kumananda Acharya, Nabin Karmacharya, Rajan Kumar Dahal, Harish C Upreti, Basistha P Rijal

Incidence and antibiogram of Vibrio cholerae from Kathmandu University Hospital, Kavre, Nepal
Ganesh P Neupane, Ramesh K Makaju, Navin K Thakur, Surendra K Madhup, Nhuchhe R Tuladhar

Clue cells’ in bacterial vaginosis
Ganesh P Acharya